Open Data and Sources

1) You can download the data used in this study from http://neuropoly.pub/pigHeartsData

2) You can let MATLAB download the data and repeat the statistical analysis.

Access source code on GitHub: http://neuropoly.pub/pigHeartsSrc

Simply run pigExvivo.m (under MATLABSource folder) main script. This will:

Explore data with interactive figures.


1) How quantitative metrics vary over weeks ?

You can use buttons on the left to navigate through the data.

For example, see how diferent cardiac T1 mapping methods (MOLLI, SHMOLLI and SASHA) consistently over- or underestimate T1 values at all weeks with respect to the reference Inversion Recovery (IR) technique.


2) Voxelwise distribution of myocardial T1 values


We selected a representative sample (Heart #2) to display how voxelwise distribution of myocardial T1 values differs from method to method and to observe their evolution over weeks.

Masked myocardium can be visualized in the Jupyter Notebook.

Observe box and whiskers plots by selecting a week using the buttons on the left.

3) Comparing T1 mapping methods in one figure


You can use the legend on the right of the figure to show/hide traces. Double click on the legend to isolate one trace, double click to reset.

4) Comparison of T1 Bias between MOLLI, SHMOLLI and SASHA before and after fixation.


T1 Bias (ms) values are obtained by subtracting reference IR maps from those acquired by MOLLI, SHMOLLI and SASHA.

5) Association between T1 Bias and MTR and T2 based on phantom acquisitions.


T1 bias (ms) values are obtained by subtracting reference IR maps from those acquired by MOLLI, SHMOLLI and SASHA.

6) Association between T1 Bias and MTR and T2 based on phantom acquisitions.


7) Association between T1 Bias and T2 & T1 Bias and MTR


T1, T2 and magnetization transfer effects are not decoupled from each other. This intertwined interaction is region variant.

Here, we explore the strength of association between the imperfections of cardiac T1 mapping techniques MOLLI, SHMOLLI and SASHA and i) T2 (Fig. 4.1) & ii) MTR (Fig. 4.2)in ex-vivo pig myocardium, by taking IR T1 mapping as a reference.


How to read these figures?

Vertical axis represents the difference between cardiac T1 mapping techniques of [MOLLI, SHMOLLI and SASHA] and reference IR. Horizontal axes traverse T2 (Fig. 4.1.) and MTR (Fig 4.2.) values.


8) Association between Native T1 and T2 & Native T1 and MTR